K a r y o t y p e . W e b Q u e s t (Best viewed at 1024x768 Resolution)

Introduction

Genetic diseases can be caused by having too many or not enough chromosomes, having extra or missing pieces of chromosomes, or having chromosomes with mixed up genetic material. Scientists have identified over 4,000 diseases that are caused by such mistakes in the human genetic code, also known as DNA. Each person is likely to have multiple mistakes in their own DNA, however not everyone has a disease. In order for doctors and scientists to determine if an individual is suffering from a genetic disease, they will run a variety of tests. One common genetic test is called a karyotype.

A normal human karyotype shows 46 chromosomes, which includes 22 pairs of autosomes and two sex chromosomes. As we have learned throughout our genetics unit, each individual gets half of their DNA from their mother and the other half from their father. However, sometimes errors occur and cause abnormalities in offspring.

For this webquest, you will learn about karyotypes and complete online activities to simulate the karyotyping process. You will also analyze karyotypes to determine whether or not patients suffer from genetic diseases.

Introduction Task Process & Resources Evaluation